Targeted-Alpha-Therapy (TAT11)


Lionel S. Zuckier, MD, MBA, FRCPC, Guest Editor

Dear colleagues,

As Guest Editor of the proceedings volume, I am pleased to present this collection of up-to-date papers which review basic science and clinical topics in the burgeoning field of targeted alpha-particle therapy (TAT). This collection has been assembled as a memorialization of the highly successful Targeted Alpha Therapy (TAT11) conference, held April 1-4, 2019 in Ottawa, Canada. TAT11 was jointly organized by Canadian Nuclear Laboratories and TRIUMF and continues a successful series of international bi-annual symposia on this topic initiated by the Joint Research Centre of the European Commission in 1997.

Included in this collection are:

  • Short Reviews of selected plenary sessions from the TAT11 meeting which provide an overview of the newest developments in preclinical studies, dosimetry and instrumentation, quality assurance, regulatory developments, targeting, radiochemistry, and nuclide production and supply, presented by invited experts in their respective fields.
  • Research abstracts of papers presented at the meeting
  • An invited review of radionuclides used in alpha therapy, which is intended to serve as a reference appendix for this volume and beyond

As a fascinating historical piece, we are also privileged to include a reprint of a scholarly article authored by Dr.M. Donald Blaufox, MD, PhD, a renowned nuclear medicine physician and medical collector, reviewing radium-containing artefacts used for medical treatments at the turn of the last century, with a short update from the author. I am sure this ‘look back’ will be appreciated by those individuals who have currently embraced alpha therapy as a therapy of the future.

I would like to thank my coworkers on the Scientific Committee (with a shout-out to Valery Radchenko and Ran Klein who organized the abstracts, and all the cochairs), the conference organizing staff (especially Denys Elliot), the JMIRS editorial staff and leadership (notably Carly McCuaig), and especially the presenters and authors, for contributing to successful completion of this proceedings volume.

Lionel S. Zuckier, MD, MBA, Guest Editor